目的:采用数据挖掘技术探究针灸治疗反复移植失败的选穴规律。方法:计算机检索CNKI数据库、万方数据知识服务平台、维普中文期刊服务平台、PubMed、Web of Science及Embase数据库中自建库至2023年2月7日针灸治疗反复移植失败的临床文献,收集处方后建立数据库,进行描述性分析、穴位关联规则分析与聚类分析。结果:共纳入文献37篇,拆分得到67条处方,高频使用腧穴(频次≥25次)包括子宫、三阴交、足三里、关元等12个腧穴,多为五输穴、交会穴、募穴、背俞穴等特定穴,使用频次居于前3位的经脉为足太阳膀胱经、任脉、足阳明胃经,多使用下肢、下腹部及背部腧穴。关联分析中所有穴组均由子宫、三阴交、足三里、关元组成,聚类分析可划分为3个腧穴群。结论:针灸治疗反复移植失败以补肾通阳、调肝健脾、养血化瘀为治疗原则,重视阳经及气血充盈经脉的使用,强调近处选穴及辨证循经取穴,选择子宫-三阴交-足三里-关元为核心穴组,与膀胱经腧穴前后相配、与肝脾肾经分布在四肢远端的穴位远近相配以提高疗效。
薄型子宫内膜,是由于多种原因导致子宫内膜受损、变薄,子宫内膜容受性降低的一种疾病,其发病率不断增加,与女性年龄密切相关。薄型子宫内膜降低对受精卵的容受能力,给越来越多育龄期妇女带来困扰以及较大的经济压力。针灸具有调补冲任,补肾健脾疏肝等重要作用,在改善子宫内膜容受性方面疗效优越。针灸治疗具有性价比高、疗效好、安全性高、患者接受度高等优势。本文将从子宫内膜、子宫内膜容受性、激素水平以及分子生物学四个方面,探讨针灸通过改善子宫内环境治疗薄型子宫内膜的临床进展,概述如下。Thin endometrium, a condition in which the lining of the uterus is damaged and thinned for a variety of reasons, with reduced endometrial receptivity, is increasing in prevalence and is closely related to a woman’s age. Thin endometrium reduces the ability to accommodate a fertilized egg, causing distress and financial stress to an increasing number of women of childbearing age. Acupuncture has an important role in tonifying Chong Ren, tonifying the kidneys, strengthening the spleen and dredging the liver, and has superior efficacy in improving endometrial receptivity. Acupuncture treatment has the advantages of cost-effectiveness, efficacy, safety, and patient acceptance. In this paper, we will discuss the clinical progress of acupuncture in treating thin endometrium by improving the intrauterine environment from four aspects: endometrium, endometrial tolerance, hormone level and molecular biology, as summarized below.
