Radiation damping effects induced by the dominated solvent in a solution sample can be applied to suppress the solvent signal. The precession pathway and rate back to equilibrium state between solute and solvent spins are different under radiation damping. In this paper, a series of pulse sequences using radiation damping were designed for the solvent suppression in nuclear magnetic resonance （NMR） spectroscopy. Compared to the WATERGATE method, the solute signals adjacent to the solvent would not be influenced by using the radiation damping method. The one-dimensional （1D） ^1H NMR, two-dimensional （2D） gCOSY, and J-resolved experimental results show the practicability of solvent suppression via radiation damping effects in 1D and 2D NMR spectroscopy.
