为了解北京地区出境人员泌尿生殖道沙眼衣原体(Chlamydia Trachomatis Infection of the Genitourinary Tract)感染的发病情况和发病趋势,给泌尿生殖道沙眼衣原体感染的防治提供指导建议,本次调查收集了2019年6月—2023年6月在北京地区进行出境体检的5286例尿液样本,利用PCR荧光探针法对沙眼衣原体(Chlamydia Trachomatis,CT)核酸进行检测,并对结果进行分析。研究结果显示,5286例检测样本中共139例泌尿生殖道沙眼衣原体检测阳性,占2.62%,其中男性阳性率为2.61%,女性阳性率为2.64%。泌尿生殖道沙眼衣原体检测阳性患者的年龄分布主要集中在21~50岁,共103例,占阳性患者总数的72%。结果表明,泌尿生殖道沙眼衣原体感染呈现较高的隐性感染率,应该加强对易感人群泌尿生殖道沙眼衣原体的筛查,减少疾病的传播。
目的:研究维生素D对于女性泌尿生殖道沙眼衣原体感染的应用疗效分析。方法:搜集2023年1月至2024年1月就诊于我院的检测出沙眼衣原体阳性的患者40名,同时选择健康的志愿者40名作为对照组。分别抽取两组患者的血清羟基维生素D(25-(OH)D)的浓度进行对比,其中感染组的患者抽取血清前未进行相关治疗;对感染组患者进行治疗结束后的1个月的血清羟基维生素D(25-(OH)D)的浓度进行检测,对比治愈患者前后血清羟基维生素D(25-(OH)D)的浓度。结果:① CT感染组与健康组的血清25-(OH)D水平进行对比,两组间比较差异有统计学意义(P 0.05);② 将治愈患者与未治愈患者的血清25-(OH)D水平进行对比,治愈患者血清25-(OH)D水平为41.37 ± 21.03,未治愈患者血清25-(OH)D水平为29.47 ± 16.66,两组间比较差异有统计学意义(P 50 nmol/L者相比维生素D水平缺乏者的调整OR = 7.188,95%CI: 2.462, 21.147。结论:人泌尿生殖道沙眼衣原体感染及疗效降低与维生素D缺乏相关,血清维生素D水平降低可能会增加泌尿生殖道沙眼衣原体感染风险,并降低疗效。Purpose: Study of the efficacy of vitamin D in the application of Chlamydia trachomatis infection of the genitourinary tract in women. Method: Forty patients who tested positive for Chlamydia trachomatis and 40 healthy volunteers were collected from January 2023 to January 2024, and 40 healthy volunteers were selected as the control group. The serum hydroxyvitamin D (25-(OH)D) concentrations of the two groups of patients were extracted for comparison, in which the patients in the infected group did not undergo any relevant treatment before serum extraction;the serum hydroxyvitamin D(25-(OH)D) one month after the completion of treatment, and ere compared between before and after the cure of the patients. Result: ① The serum 25-(OH)D levels of the CT infected group were compared with those of the healthy group, statistically significant (P 50 nmol/L. Conclus